On Wednesday demonstrators were responding to the recent slaughter of 21 Egyptian Coptic Christians by IS militants in Libya, according to Middle East Online.
"We want to express solidarity with Egyptians and Copts, and to show how sad Palestinian Christians and Muslim friends are" about the deaths, said Nashat Filmon, 39.
"It doesn't make up for the barbaric way they were slaughtered, so we pray for this region to wake up and reject (IS)," he said.
Joseph George, 25, said the international community should intensify its fight against the group.
"If the US could destroy Saddam Hussein's regime in a week, why can't they do it to a small group?" he asked.
"Christianity originated in the Middle East, but now there's no more place for us - we've been fleeing for years.
"Jesus taught us to turn the other cheek... but if someone tries to kill you for no reason, you should defend yourself."
On the same day Barack Obama called on Muslims around the world to fight the misconception that groups like the Islamic State speak for them.
At a White House summit on countering violent extremism, the US president asked Muslims to "do more" to distance themselves from brutal ideologies.
