Fr Luis Roldan Patino from Spain said he had given up hoping the local authority would fix the holes in the road which had blighted locals for months.
Speaking at a service in his church in Xestoso, north western Spain, he appealed for prayers.
After celebrating Mass he splashed holy water on a pot hole covered road.
Each pothole is now marked with a wooden cross at the roadside so drivers can slow down before hitting them, he said.
The priest told journalists that "just like we can pray to the Lord for rain" he is pleading for divine intervention to fix the road because "it's going to be the only way to do that".
Authorities are "blind to the situation and we feel totally abandoned", he said.