The Ballyclare Free Presbyterian Church had its windows smashed in the latest incident.
It is believed to have occurred overnight between 28th and 29th December.
While no arrests have been made, the police have discussed anti-social behaviour and criminal damage in the town centre with members of the community.
In a Facebook post, an officer asked: "Parents, do you know where your young ones are of an evening?
"Please have a word before we end up with an arrest charge and court appearance."
Anyone who saw suspicious activity around the church in recent days should contact police on 101.
Stay up to date with the latest news stories from a Christian perspective. Sign up to our daily newsletter and receive more stories like this straight to your inbox every morning.
