Gunmen hiding in a mini bus shot at Christians leaving the Church of the Angel Rafael in Alexandria.
One of the injured was a police officer who was thought to have been guarding to church.
The militants fled the scene and have yet to be caught.
Elsewhere yesterday Islamic militants also detonated a bomb in the Egyptian capital Cairo (pictured).
Egypt has been struggling with an increasing Islamic insurgency after the ousting of president Mohamed Morsi in 2013.