The leader pointed to moves by his administration to stem the flow of federal funding to abortion clinics and work to secure the freedom of imprisoned church leaders such as Andrew Brunson - who has been held in Turkey since October 2016.
Speaking at a dinner held at the White House on Monday night, he was quoted by the Washington Times as saying: "The support you've given me has been incredible.
"But I really don't feel guilty because I have given you a lot back, just about everything I promised."
Mr Trump welcomed several high-profile Christian figures for the formal occasion, including Rev Franklin Graham and president of the Christian university Liberty, Jerry Falwell Jr.
Megachurch leader Paula White and James Dobson from the Christian conservative organisation Focus on the Family also attended.
At tonight's White House evangelical dinner, Paula White presents a Bible to @POTUS and @FLOTUS , signed by over 100 Christians and inscribed with a quote. Read here. @CBNNews @WhiteHouse @realDonaldTrump pic.twitter.com/YgMkHwwnsR
— David Brody (@TheBrodyFile) August 28, 2018
The US President also said "attacks" on faith communities throughout the US were "over", citing efforts to protect freedom of conscious and religious liberty.
He added: "Unlike some before us, we are protecting your religious liberty.
"We're standing for religious believers, because we know that faith and family, not government and bureaucracy, are the center of American life.
"And we know that freedom is a gift from our Creator."
In January, the US government announced a new division within the Office of Civil Rights at the Department of Health and Human Services to help safeguard medical staff who object to performing certain procedures, such as abortions.
Stay up to date with the latest news stories from a Christian perspective. Sign up to our daily newsletter and receive more stories like this straight to your inbox every morning.