The Dean of York, Rt Rev Dr Jonathan Frost, has been appointed as the new Bishop of Portsmouth succeeding Rt Rev Christopher Foster, who retired in May.
The Queen has officially approved his nomination.
Bishop Jonathan will lead the Church of England's Diocese of Portsmouth, which covers 133 parishes across southeast Hampshire and the Isle of Wight.
His current role involves leading the historic York Minster, where he has served since February 2019.
The Archbishop of York, Most Rev Stephen Cottrell, has described him as "an outstanding Dean of York".
"Although we are very sad to see him go, we are delighted that he has been called to use his considerable gifts of leadership, pastoral care and missionary endeavour as the next Bishop of Portsmouth."
Bishop Jonathan said: "I believe the role of a bishop is to pray, to share the story and the love of Jesus, and to speak up for the marginalised and voiceless.
"I've got Portsmouth on my heart. Many people across this diocese have had a tough time through the pandemic, especially the most vulnerable, and I know Christians here played their part with others to support those in need.
"I'm looking forward to working in partnership, as together we tackle the biggest issues facing us today - such as the poor mental health and wellbeing of so many of our young people; climate change; and the scandal of poverty, which restricts opportunities and life chances.
"I am, of course, sad to be leaving York Minster and valued colleagues there. It's a real privilege to be called to the work God is doing in south-east Hampshire and the Isle of Wight."
The Archbishop of Canterbury, Most Rev Justin Welby, said: "I'm so pleased that Bishop Jonathan has accepted this invitation to become the next Bishop of Portsmouth.
"His wide range of interests and experiences, from youth engagement and interfaith relations to social justice and community building will be invaluable in bringing the people of Portsmouth together as he begins this new role. Please join me in praying for him and his wife Christine as they take this next step in their journey as disciples of Jesus."