The two teams squared off at Kent County Cricket Ground in Canterbury last September in a historic match to raise money to tackle slavery and human trafficking.
The Anglican side triumphed but now the Vatican side wants another chance at success on its home soil.
They're hoping for a better performance after the Archbishop's XI lifted the trophy last year by six wickets with five balls to spare.
A Church of England side will travel to Rome on Wednesday 21 October, where it is expected they will meet Pope Francis.
The match itself - Twenty20 - will take place on Sunday 25 October, at the end of the Roman Catholic Church's Synod on the Family.