Dozens are thought to have been killed in the latest quake so far. It's after a previous earthquake last month, which has killed more than 8000 people so far.
Catholic Relief says Christians need to come together to show their support.
Jen Hardy is from the charity. In Nepal, she told Premier: "I was talking to a man in a different village a couple of days ago, and I was asking him, where do you get your hope?
"This is a long road to go before things start to get better for your family - he's suffered a few tremendous losses.
"And he said honestly, it's seeing people from the outside, like you that makes me feel like the world hasn't forgotten us."
She stressed the importance of prayer during this difficult period: "I really think that Christians around the world if they can band together in support in times or crisis and when people are at their lowest point, it's actually an amazing thing.
"And people here in Nepal especially are really appreciating the attention and support the international community and faith communities are giving."
She said that people were horrified when the tremors began: "I was holding one little grandma crying as the earthquake happened, there was no one else around, she lived alone, so I was with her when the earthquake was going on.
"So even if logically people knew they were safe, they were still really afraid and crying."
Listen to Premier's Hannah Tooley speak to Jen Hardy here:
