Thomas Aquinas College in Santa Paula said on its website that flames "came up to the very edge of the campus access road".
The school's 350 students were asked to go to their own homes or to those of faculty and staff.
*** THOMAS FIRE UPDATE: CLASSES CANCELED ALL WEEK *** pic.twitter.com/wpdJQcat3L— ThomasAquinasCollege (@TACollege) December 6, 2017
The blaze, known as Thomas Fire, started on Monday evening and quickly spread to several homes.
While it caused extensive damage to trees and brush on the campus, it only left minor damage to the school's coffee shop patio.
The threat to the campus has subsided, but it has been left without power and has cancelled classes for the rest of the week.
Thomas Aquinas College has asked for prayers for the safety of all those affected by the fire.
The California wildfires have destroyed 200 homes prompted evacuation orders for at least 150,000 people.
At least two people have been injured.