The United States Conference of Catholic Bishops' (USCCB) Subcommittee on the Church in Africa is giving more than $1.2m (almost £800,000) in grants towards supporting pastoral projects for the church branch.
The projects will focus on providing support for the fast-growing Catholic Church in Africa, including caring for migrants, refugees, children and those living in poverty.
Money will also to be spent on leadership programmes as well as faith-building programmes and schemes to strengthen families.
Cardinal Theodore McCarrick, Archbishop Emeritus of Washington and chairman of the Subcommittee on the Church in Africa, said: "The Church in Africa is fully alive and developing at a rapid pace.
"It is vital to assist Catholics there by providing urgently needed pastoral support.
"The people of Africa greatly benefit from proper training in pastoral care, leadership, and management.
"The support from the Church in the United States is integral to helping the Church in Africa become self-sustaining and meet the spiritual needs of its people."
One part of the funding is going towards Angola.
The Archdiocese of Luanda and the Dioceses of Viana and Caxito received a grant to help create workshops, training and retreats for pastoral workers, as well as training for migrant communities in different languages.
The aim is to better integrate newcomers to the local parish.
Liberia is another country receiving funding to establish a women's organisation for Catholics.
It aims to promote women's rights within church and society, and train females in leadership skills.
The grants are funded by donations from an annual collection for the Solidarity Fund for the Church in Africa.