It is understood that Herzel Brewey in Jerusalem was given 5kg of wheat which was the same strain used to brew beer in the Holy Land 2,000 years ago.
The business used the donation of grain from geneticists at Tel Aviv University to produce 20-litres of the beverage which has a three per cent alcohol content, one news agency has said.
Herzl's owner, Itai Gutman, told Reuters: "We were curious about being able to come up with the first 'biblical' beer. It's really not the kind of flavour that has a market."
While wine is frequently mentioned in the Bible and features in Communion, it is thought Jesus and his disciples would have been familiar with beer.
Studies suggest that beer first emerged in Israel after it was imported from Egypt by the ancient Israelites.