The son of Billy Graham has been speaking as Theresa May battles to keep her role as Prime Minister.
She's facing a vote of no confidence on Wednesday evening.
Writing on his social media pages, Franklin Graham called on his followers to pray.
He said: "The UK is going through a political crisis. I'm asking Christians to pray for PM @theresa_may, Members of Parliament, & all of their leaders. Pray that God would give them wisdom & direction as they make decisions that will impact the lives of so many.
"Prayer is powerful - it gives us direct access to Almighty God. His Word instructs us to pray for, 'all those in authority, that we may live peaceful and quiet lives in all godliness and holiness'."
His comments come after he visited the UK in September for a mission in Blackpool.
He's due to return for a speaking tour in 2020.