A 17-year-old boy and two men, aged 18 and 20, attacked on New Year's Eve, along with a 20-year-old man knifed in the early hours of the following morning, all died as a result of their injuries, while a fifth victim is critically ill in hospital.
Six suspects have been arrested and Metropolitan Police have called the situation "truly unusual and extraordinary".
Michael Smith is founder and CEO of Words for Weapons, a Christian organisation that helps tackle knife crime by collecting knives and holding knife crime education workshops.
He told Premier the war on knife crime needs more input from everyone.
"It needs more work from the community, from the police, and from the government. "It needs more funding, thought and work put into it," Smith said.
"I hope that churches and other organisations will step up to the plate do something positive in the community about it."
Smith also made a plea for churches to use more of their resources to help combat the issue.
He told Premier: "There are many areas where young people need help; they need someone they can have confidence in and express their struggles and challenges to.
"I find on too many occasions our churches are closing up the church doors during the week except for Bible class, prayer meeting and services on Sunday.
"These are buildings that God has given us and we need to occupy them and make them available. The church should be a place of safety to provide that secure environment."
He also urged Christian to pray for children "that have no spiritual or moral guidance or compass".
