Joined by the Duke of Edinburgh, Her Majesty will attend a service at Westminster Abbey to mark the inauguration of the Tenth Synod. Each synod lasts five years.
It will be presided over by the Archbishop of Canterbury Most Revd Justin Welby and a sermon will be delivered by Father Raniero Cantalamessa, Preacher to the Papal Household.
After the service the Queen will make her way to the inauguration ceremony in Church House, the Westminster headquarters of the Church of England.
General Synod is the Church's national assembly which decides canon law and other matters of importance to the faith.
It has powers to pass measures which, if approved by resolution of each House of Parliament, receive Royal Assent and thereby become part of the law of England.
The main debate will be about how Britain responds to the refugee crisis.
There will be two main areas of discussion: how many refugees Britain should be taking and whether there should be a preference towards Christians facing persecution.
Sources say there was tension on the two issues that would need to be resolved at the Synod.
Elsewhere it was announced the gender imbalance on Synod had decreased again. This year 58% elected were men and 42% female.
For the first time ever there are more elected woman than men in the House of Laity.
