The dolls have been made to imitate the Barbie toys and show Mary with a baby Jesus, while the male version is Jesus Christ on the cross.
Makers Pool Paolini and Marianela Perelli said they were to be named 'Barbie, The Plastic Religion' and would be exhibited in Buenos Aires from October 11th.
They said: "If there's a Barbie doctor, a teacher and a police officer, why shouldn't there be a Virgin of Lujan Barbie?"
The duo also created 33 Barbie and Ken dolls for religions including Catholicism, Judaism, Buddhism and Islam.
On Facebook the pair said: "In a world where we're rewarded for thinking, feeling and acting all the same, Marianela and Pool set themselves apart by rebelling.
"Through humour, they highlight a fictional, historical, religious, political universe where their elders are trapped."