The Democratic presidential nominee spoke at church services in Charlotte, North Carolina, which has been grappling with last month's shooting of a black man by a police officer.
Ms Clinton said at Little Rock AME Zion Church that the country should try to imagine gun violence "through our children's eyes".
She was joined at the pulpit by nine-year-old Zianna Oliphant.
The African American youngster recently gave a tearful address to the city council on race relations, saying she could not "stand how we're treated".
The shooting of Keith Lamont Scott led to two nights of protests, both peaceful and violent, in the centre of Charlotte (below).