Rev Kate Bottley, BBC Songs of Praise presenter and Gogglebox commentator, is going to lead the Church of England's national online broadcast this week from her home.
She is particularly hoping to welcome viewers who have not taken part in virtual worship before and encourage them to join in where they can. The sermon will be delivered by Christian Aid's Chine McDonald.
She will pray for people who are suffering and bereaved as a result of the coronavirus pandemic.
Prayers will also delivered in British Sign Language by Carolyn Denmark, of St Barnabas Parish Church in Swindon, Wiltshire, who is deaf herself, and will pray for the needs of the deaf community. She will further pray that God will guide scientists, the Government and the NHS in their efforts to treat patients and stop the spread of the disease.
The Church of England's weekly online services are averaging 500,000 - 600,000 viewers each week.
Kate Bottley said of this week's: "We are as a nation conscious of the challenges and problems in the world at the moment, and the joy of the risen Christ can often feel far away,
"Anyone can join us at this service and all those taking part for the first time are especially welcome. I hope that the prayers that are offered and the message of the gospel will go some way to help all those seeking comfort and support at this difficult time."
Ms McDonald will speak of the need to support those living in poverty around the world who face dealing with the virus while lacking even basic medical care, food and water: "As coronavirus infection rates speed-up in poorer countries, it will put a massive strain on already fragile health systems. This will be catastrophic.
"Coronavirus impacts all of us. But love unites us all. Love always protects, always trusts, always hopes, always perseveres. Love never fails. Even in the darkest moments, love gives hope. Love compels us together around the table, to stand together, elbow to elbow in solidarity with our neighbours near and far."
The service will be available from 9am on Sunday on the Church of England's website, Facebook page and on YouTube.