The Children's Society in Dorset won money from the Department of Education 2016-2018 grant aimed at tackling the abuse of vulnerable youngsters.
Eight other grassroots groups also got funds to help in the battle against female genital mutilation and radicalisation.
Education Secretary Justine Greening hoped the projects which work with children, young people and their families, as well as schools, communities and social care professionals, would "make a real difference".
She said: "This funding will help us to support families that have experienced domestic violence, as well as helping to prevent abuse occurring in future.
"It's people working with the most vulnerable in our society on the ground who are often best placed to trial new approaches to keeping them safe, and these nine projects can make a real difference."
The Children's Society chief operating officer Val Floy said the organisation was "delighted" by the windfall, which would be used to support children living in families hit by substance misuse and domestic violence.