The comments come as the Department of Health confirmed to the Independent newspaper that a parliamentary debate on changing the law to allow the technique would almost certainly happen before the general election in May.
The technique uses DNA from two women and one man, technically giving the child three parents.
Philippa Taylor, Director of Public Policy at the Christian Medical Fellowship, told Premier: "There are a huge number of ethical and safety issues that are still not resolved and are still extremely concerning. Safety-wise it's not been proved to be safe at all.
"We are effectively going to be experimenting on babies by using these techniques.
"There are enormous safety concerns. These techniques are really different to any others that've been permitted before, because they change the germ-line and therefore impact future generations in ways that we don't know and can't predict.
"They estimate that these techniques could be used for perhaps ten women a year.
"So they're making huge changes in regulations and experimental techniques for benefiting perhaps ten women or so.
"This has never been done in any other country in the world. It's something that no other country has dared go down because people are concerned once you pass this boundary, what boundary is there left?"
Scientists in Britain have said they will carry out safety tests this year if legislation allowing the genetic technique is passed.
