Around 40 per cent of almost 1,000 doctors questioned by mental health charity Mind said they had dealt with issues, such as depression, anxiety, bipolar or post-traumatic stress disorder.
Dr Mark Pickering, a Christian prison GP in Yorkshire told Premier he wasn't surprised by the results of the poll.
"Many of my colleagues face mental health problems. The workload, the intensity of the job - it's a very stressful environment for GPs and for many people in the health service," he said during Premier's News Hour.
"I guess we often tend to focus on caring for our patients and sometimes we can neglect our own health and maybe not feel able to speak up about that."
The survey found less than half of GPs would turn to their colleagues for support if they experienced a mental health problem in the future.
However, 86 per cent said they would get support from families and friends, while 79 per cent would go to their personal doctor.
Mind welcomed existing initiatives such as a confidential NHS support service for GPs, but has called on the Government and NHS England to do more to help those affected.
Dr Pickering said Christians could also do more to support GPs.
He added: "Many of us will have GPs and other healthcare professionals within our churches and one thing you can do is just ask them 'how work is going?'
"Obviously they can't talk about confidential things but in terms of how they're managing the workload, the kinds of struggles that they face - it's great to know that other people are praying for them.
"So if you do have a Christian GP or a nurse or someone else in the health service, just ask them how they're doing, pray for them - they really appreciate it."
A Department of Health and Social Care spokeswoman said: "GPs are a vital part of the NHS and we recognise the pressures they face every day - that's why we're increasing investment by £2.4 billion a year by 2021 and recruiting 5,000 new doctors into general practice.
"The GP Health Service, launched in 2017, is a free and confidential mental health service for GPs, so they can get the help and support they need."
Listen to Dr Mark Pickering speaking with Premier's Tola Mbakwe:
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