Eamon Martin has been criticised for his comments surrounding terminations and the equal right to life for unborn babies by Campaign group Terminations For Medical Reasons (TFMR).
The senior Catholic cleric said he was trying to put Church principles across with compassion and mercy.
In a few weeks the Northern Irish citizens assembly will be discussing the issue, known as the eighth amendment.
It will be chaired by a judge and include 99 randomly selected members of the public. It was created by the Government to begin assessing whether a new referendum should be called on the eighth amendment and the right to life of the unborn.
What is the eighth amendment?
'The State acknowledges the right to life of the unborn and, with due regard to the equal right to life of the mother, guarantees in its laws to respect, and, as far as practicable, by its laws to defend and vindicate that right.'
Speaking to RTE's This Week programme, Archbishop Eamon said: "I think that we would call on politicians not to leave their faith outside of the door when it comes to issues to do with policy and public policy. The teaching is clear on this issue.
"I think if you're a Catholic and wishes to be informed by the teaching of your church you will not find in the teaching of the church a statement that says that you can support the deliberate and intentional taking of human life at any stage.
"What I'm saying is that for a Catholic who wishes to abide by the teaching of their church then they must be informed about something as fundamental as the right to life."
Archbishop Martin described the eighth amendment as precious and wonderful.
He said: "I'm aware that some people feel that the position that all human life is precious, at every stage from the moment of conception. I'm aware that some people feel that as an encumbrance.
"But nonetheless it's a fundamental principle. And it's one that we try to make with love. It's one that we try to make with a sense of mercy and an understanding of where people are at."