Those gathering will hear from speakers including Cardinal Vincent Nichols and Mike Pilavachi and will be led in worship by Matt Redman.
The Congress is the largest Catholic Youth Event in England and Wales with people travelling from across the country as well as overseas.
This year's theme is 10,000 reasons, with young people being challenged to remember refugees around the world.
Jack Regan from CYMFed, the organisation behind the event told Premier he was excited about the day ahead.
He said: "This is our third event. It's a national gathering to come together to celebrate young people in the Church.
"We want to give them something to take back to their parishes. Something reminds them who God's calling them to be and something to remind them what the important issues are in the world that they may want to get involved in."