There were 23,856 entries recorded in 2017, a small decrease of 4 per cent on the previous year.
The number is over double the entries recorded in 2003 and the fall is being explained as being linked to the decrease in the number of 18 year olds in England, Wales, and Northern Ireland of 1.7 per cent.
That said, entries for other humanities subjects Politics, Economics, Sociology, Law and Geography showed an increase in numbers.
The figures have been welcomed by those working within the subject.
Daniel Hugill, Chair, National Association of Teachers of RE said: "It is of little surprise to those of us who teach RS that it remains so popular amongst young people.
"RS A-level is an excellent preparation for both further study and for entering the world of work.
Rudolf Eliott Lockhart, Chief Executive, Religious Education Council of England and Wales said: "It's fantastic to see how popular Religious Studies A level remains.
"This is a highly rated subject that offers pupils the opportunity to explore crucial questions in relation to beliefs, values and morality.
"In doing so it provides an excellent preparation for living in a multi-faith, multi-cultural world."