The Brit says the meeting is the one thing she'd like to do before she dies.
Speaking to media outlet 'On Demand Entertainment' she said: "I want to meet the Pope...I've got two weeks to go.
"I just keep saying 'I want to meet the Pope' and then someone said 'do you want to come?' and I said 'yeah!'.
"But I didn't want to meet him in America, I wanted to meet him in his home.
"I think this Pope is absolutely amazing."
Naomi Campbell has previously spoken of her own faith.
Responding to the celebrity trend of following the Kabbalah belief system, she said she wasn't interested: "We're all looking for positivity in our lives and looking towards the light but I just believe in God.
"I am religious. I pray most days and do my thing. But each to their own."
Pope Francis has become known for hosting a number of high profile figures at the Vatican from footballers to movie stars to politicians.