The evangelist says The World Summit in Defense of Persecuted Christians will be staged from October, 28 until October 30 in Mosow, Russia.
The son of evangelist Billy Graham, Franklin Graham said: "No church in modern history has suffered more than the church in Russia.
"In the years under Communist rule, virtually all of the priests, pastors, and church leaders in Russia were imprisoned or executed by the Communists, and their graves are on the outskirts of Moscow and throughout the country serving as a reminder.
"So, Moscow will be a fitting and meaningful location for this much-needed summit.
"I was in Russia this past October and met with Patriarch Kirill, the head of the Russian Orthodox Church, and evangelical leaders, and we discussed at length the persecution of the church worldwide."
The World Summit in Defense of Persecuted Christians is set to welcome Christians from different churches and denominations to "pray for our brothers and sisters in Christ and to hear firsthand reports of the suffering taking place around the world."
Organised in partnership between the Billy Graham Evangelistic Association and the Russian Orthodox Church, the gathering will particularly drew attention to attacks on Christians in the Middle East in recent years.
Franklin Graham went on to say: "Britain's Prince Charles has warned that Christianity might be entirely erased from the land of its birth in the Middle East within five years.
"We saw beheadings, torture, imprisonment, and more in many countries around the world. The World Summit in Defense of Persecuted Christians will shed a global spotlight on this crisis.
"We will bring delegates from around the world and will be able to join hands with people of other churches and denominations of the Christian faith to pray for our brothers and sisters in Christ and to hear firsthand reports of the suffering that is taking place."