Produced by the Christian charity, Oasis, the study claims to be the first to demonstrate a link between church attitudes towards same-sex relationships, societal attitudes and poorer mental health among LGB people.
Founder, Rev Steve Chalke, said: "It is no secret that the negative stance taken by the Church, and so many individual local churches, has a hugely distressing impact on large numbers of LGB people and leaves countless numbers of them living lives of forced secrecy and dishonesty.
"Tragically, it is also common knowledge that the resultant anguish and distress often leads to spiritual, mental and physical harm, and in the worst of cases to people making the desperate decision to take their own life."
Oasis concluded LGB people are twelve times more likely to experience mental health problems including depression, anxiety, self-harm and suicide.
The research came under fire from a spokesman on issues surrounding sexuality, Rev Peter Ould, who said it doesn't prove the claims it makes.
Rev Ould said: "The paper produces no quantitative or qualitative evidence that commentary, that criticism from conservative Christian circles does itself cause mental health issues."
Oasis also accused every major UK church denomination, except the United Reformed Church, of practising some kind of discrimination against LGB people.
Rev Ould urged a cautious response but added: "We do need to think about our tone. We do need to think about whether we are in some parts obsessed by this issue and we should be moving on.
"But, at the same time, I don't think we need to be afraid or scared of this report - it does not prove the point it is trying to make."
The study found Christians are responsible for 91 per cent of the negative comments about same-sex relationships in the media, while church-going politicians are the cause of 54 per cent of political opposition to equal laws for LGB people.
Speaking about the experiences of LGB people, Steve Chalke added: "Too often however, these powerful testimonies are dismissed by those that don't want to hear them - those who are not yet ready to face up to the scale of the damage that we collectively have unintentionally caused.
"My hope is that this report is the beginning of a sea change to this approach."
Click here to listen to Rev Peter Ould speaking with Premier's Marcus Jones: