It said students who weren't happy with their results shouldn't panic, and that many options were still available to them.
It used the example of colleges, saying they may be flexible with course requirements, and suggested students could enrol on a different course or apprenticeship, enter the world of work, or volunteer for a year to gain experience.
It's National Advisor for Further Education, Garry Neave, said employers are just as interested in personality as they are in GCSEs.
He told Premier's News Hour: "The hardest thing of all is: try not to panic too much. It probably feels like the end of the world, you'll never get to the college or sixth-form you wanted to, your career's over forever - it's not like that."
"Employers often are just as concerned about the kind of person you are, as what qualifications exactly you got when you were 16 or 17.
"They're not the only thing for the rest of your life that people are going to be looking at."
The number of students achieving C grades or above in the GCSEs rose slightly from last year, by 0.2%.
However the amount of students getting A* grades also fell for a fourth year in a row, by 0.1%. Just under seven percent of all GCSEs were A*s.
Listen to Premier's Antony Bushfield speaking to Garry Neave on the News Hour: