Jack Phillips - owner of the Masterpiece Cakeshop in Lakewood, Colorado - is being sued by state officials who allege he broke discrimination laws by refusing to make a cake celebrating transgenderism.
He successfully defended his right to decline a request that he cater for a same-sex wedding during a high-profile case against the Colorado Civil Rights Commission (CCRC) at the nation's highest court last summer.
Asked whether he was prepared for his latest legal battle involving the Commission to reach the US Supreme Court, he said: "The first fight was worth the fight and this one is too. The cases are so similar."
The CCRC began new legal proceeding against Phillips after he refused in 2017 to decorate a cake celebrating the gender transition of lawyer Autumn Scardina.
The Commission deemed there was "probable cause" to believe he was legally obliged to produce the cake - which would have been blue on the outside and pink in the middle.
But, earlier this month, a federal district court gave Phillips the go-ahead to counter-sue the State of Colorado on the grounds of hostility against him and his religious beliefs.
During a high-profile case at the US Supreme Court last summer, justices ruled - with seven votes to two - that Phillips was within his rights in 2012 to decline an order from two gay men for their wedding.
Jack Phillips said: "This case was addressed by the United States Supreme Court; the Colorado Civil Rights Commission was told that it was being hostile to my faith.
"They can't do that - their doing the same thing again - and they have to treat me equally with other bakeries."
Jack Phillips is being supported by the Christian legal firm Alliance Defending Freedom.
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