Patriarch Kirill said the Church does not oppose technological advancements but the internet-connected devices created the possibility for "universal control over humanity".
During an interview on Russian state television, he said the gadgets allow someone to know "exactly where you are, know exactly what you are interested in, know exactly what you are afraid of".
He continued: "Such control from one place forebodes the coming of the Antichrist.
"The Antichrist is the person that will be at the head of the world wide web controlling all of humanity. That means that the structure itself poses a danger.
"There shouldn't be a single centre, at least not in the foreseeable future, if we don't want to bring on the apocalypse."
Christians tend to regard the Antichrist as the polar opposite and personal opponent of Christ. His coming is counted among signs pointing to the end of the world.
Biblical warnings concerning the Antichrist are found in books including 1 John.
1 John 2:18 says: "Dear children, this is the last hour; and as you have heard that the antichrist is coming, even now many antichrists have come. This is how we know it is the last hour."
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