Rt Revd Julian Henderson, Bishop of Blackburn; Rt Revd Geoff Pearson, Bishop of Lancaster and Rt Revd Philip North, Bishop of Burnley made a joint statement following the latest flooding in the north of England.
They said: "Communities across the County of Lancashire and in other parts of northern England have once again been affected by unprecedented levels of rainfall leading to flooding and evacuations from homes in villages such as Ribchester and Whalley.
"Coming so soon after the last floods, these incidents, occurring during the Christmas period, led to untold hardship for many as they struggled to defend their homes against the unprecedented rising water levels.
"Our thoughts and prayers are with all those who have had to leave their homes at a time of year when they should be relaxing in those homes with their families and friends."
They were speaking as the Prime Minister, David Cameron, prepares to visit stricken communities as swamped towns and cities continue to struggle against the Christmas floods.
More rain is forecast for the middle of the week and the Environment Agency has more than 25 severe flood warnings in place, meaning there is still a danger to life.
The worst-hit areas will have some rest from rain on Monday but the crisis looks set to continue as more bad weather sweeps in.
On Wednesday up to three inches of rain (80mm) falling on high ground and potentially in excess of 4.7ins (120mm) in exposed locations is expected.
Some 500 military troops have been mobilised to aid emergency services, with another 1,000 on standby should the situation worsen and the Met Office has issued yellow warnings for rain on Wednesday in North West England, North East England, Yorkshire and Humber, Wales and Northern Ireland.
The Bishops from the Diocese of Blackburn continued: "Our thoughts and prayers are also with those who are facing disruption in power supplies and with anyone whose lives have been affected in any way by the floods.
"As with the previous floods earlier in December, the emergency services and the army have worked tirelessly to ensure the safety of those affected and we pay tribute to their steadfastness in this time of trial. We hope everyone in the worst affected areas will cooperate fully with their instructions and will draw strength from their presence.
"There are also numerous volunteers, including volunteers from local faith communities, doing what they can to alleviate the situation. We hope people will continue to pull together.
"At this time of year we remember the birth of Jesus, our Emmanuel, which means 'God with us'. In Psalm 46, v1 it says 'God is our refuge and strength, an ever-present help in times of trouble'. We hope people will draw comfort from these words at this difficult time."
The Government has also vowed to look again at the quality of the UK's flood defences as home and business owners face up to a miserable start to the new year.
Emergency financial assistance will also be put in place for affected areas, and homes and businesses damaged by flooding will have access to the same package of support announced for those affected by Storm Desmond.
Mr Cameron praised the efforts of the emergency services and said that with the prevalence of such extreme weather events on the rise, investment in flood defences would continue.
Many places have seen record river levels over the past 24 hours, including the River Aire in Leeds, and the rivers Calder and Ribble, affecting places such as Whalley, Hebden Bridge and Ribchester.
